POS1385 AUTOIMMUNE DISEASES ASSOCIATED WITH CHRONIC LIVER DISEASES

Background: Chronic liver diseases whatever their etiologies could be associated with immunological disturbances. Objectives: Our aim was to evaluate the prevalence and characteristics of autoimmune chronic diseases. Methods: We performed a retrospective analysis data from consecutive patients followed in our department for recruited January 2010 December 2019. Demographic, clinical, paraclinical were collected. Results: A total 224 included. The mean age 61.02 ±13.2 years sex-ratio 1.6. main etiology viral infection C (32.1%) by B (22.8%) non-alcoholic steatohepatitis (21.4%). 7.58%: hepatitis (AIH) four cases, primary biliary cholangitis (PBC) huit sclerosing (PSC) three cases overlap syndrome (AIH-PBC) two cases. Autoimmune noted 31 (13.9%): hemolytic anemia 15 thyroiditis 12 one case psoriasis, CREST syndrome, Sjögren’s thrombocytopenia. pathologies more disease than other causes (47% vs 11.1%, p <0.001). not statistically female gender (p = 0.085) or young 0.483). Conclusion: In study, during 13.9%. This higher (47%), which would underline importance systematic screening clinical biological immune manifestations those patients. Disclosure Interests: None declared